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2-Amino-6-(piperidin-1-yl)-4-p-tolyl-pyridine-3,5-dicarbo-nitrile.

ABSTRACT: In the title compound, C19H19N5, the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039?(2)?Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90?(14) and 56.10?(12)° with the piperidine and benzene rings, respectively. In the crystal, mol-ecules are linked via N-H?N and C-H?N hydrogen bonds, forming chains along [101], and enclosing R 2 (2)(17) ring motifs. The chains are linked by further C-H?N hydrogen bonds, forming two-dimensional networks lying parallel to (10-1), and enclosing inversion dimers with R 2 (2)(20) ring motifs.

SUBMITTER: Inglebert SA

PROVIDER: S-EPMC3885062 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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2-Amino-6-(piperidin-1-yl)-4-p-tolyl-pyridine-3,5-dicarbo-nitrile.

Inglebert S Antony SA Kamalraja Jayabal J Sethusankar K K Vasuki Gnanasambandam G

Acta crystallographica. Section E, Structure reports online 20131123 Pt 12

In the title compound, C19H19N5, the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 (14) and 56.10 (12)° with the piperidine and benzene rings, respectively. In the crystal, mol-ecules are linked via N-H⋯N and C-H⋯N hydrogen bonds, forming chains along [101], and enclosing R 2 (2)(17) ring ...[more]

PMID: 24454238

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