Ontology highlight
ABSTRACT:
SUBMITTER: Dixit AB
PROVIDER: S-EPMC3903156 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Dixit Aparna Banerjee AB Ray Krishanu K Thomas Julie A JA Black Lindsay W LW
Virology 20130907 1-2
Bacteriophage ATP-based packaging motors translocate DNA into a pre-formed prohead through a dodecameric portal ring channel to high density. We investigated portal-terminase docking interactions at specifically localized residues within a terminase-interaction region (aa279-316) in the phage T4 portal protein gp20 equated to the clip domain of the SPP1 portal crystal structure by 3D modeling. Within this region, three residues allowed A to C mutations whereas three others did not, consistent wi ...[more]