Ontology highlight
ABSTRACT:
SUBMITTER: Zevnik B
PROVIDER: S-EPMC3944090 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Zevnik Branko B Uyttersprot Nathalie C NC Perez Ana V AV Bothe Gerald W M GW Kern Heidrun H Kauselmann Gunther G
PloS one 20140305 3
We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells. ...[more]