Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor.
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ABSTRACT:
SUBMITTER: Bonham AJ
PROVIDER: S-EPMC3956051 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor.
Bonham Andrew J AJ Paden Nicole G NG Ricci Francesco F Plaxco Kevin W KW
The Analyst 20131001 19
We describe an electrochemical analog of fluorescence polarization that supports the quantitative measurement of a specific protein, the chemokine IP-10, directly in undiluted blood serum. The sensor is label-free, wash-free, and electronic, suggesting it could support point-of-care detection of diagnostic proteins in largely unprocessed clinical samples. ...[more]
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