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A dual site catalyst for mild, selective nitrile reduction.

ABSTRACT: We report a novel ruthenium bis(pyrazolyl)borate scaffold that enables cooperative reduction reactivity in which boron and ruthenium centers work in concert to effect selective nitrile reduction. The pre-catalyst compound [?(3)-(1-pz)2HB(N = CHCH3)]Ru(cymene)(+) TfO(-) (pz = pyrazolyl) was synthesized using readily-available materials through a straightforward route, thus making it an appealing catalyst for a number of reactions.

SUBMITTER: Lu Z

PROVIDER: S-EPMC3999263 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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A dual site catalyst for mild, selective nitrile reduction.

Lu Zhiyao Z Williams Travis J TJ

Chemical communications (Cambridge, England) 20140109 40

We report a novel ruthenium bis(pyrazolyl)borate scaffold that enables cooperative reduction reactivity in which boron and ruthenium centers work in concert to effect selective nitrile reduction. The pre-catalyst compound [κ(3)-(1-pz)2HB(N = CHCH3)]Ru(cymene)(+) TfO(-) (pz = pyrazolyl) was synthesized using readily-available materials through a straightforward route, thus making it an appealing catalyst for a number of reactions. ...[more]

PMID: 24409456

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