Ontology highlight
ABSTRACT:
SUBMITTER: Loubeau G
PROVIDER: S-EPMC4010470 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Loubeau Gaëlle G Boudra Rafik R Maquaire Sabrina S Lours-Calet Corinne C Beaudoin Claude C Verrelle Pierre P Morel Laurent L
PloS one 20140505 5
The chaperone nucleophosmin (NPM1) is over-expressed in the epithelial compartment of prostate tumours compared to adjacent healthy epithelium and may represent one of the key actors that support the neoplastic phenotype of prostate adenocarcinoma cells. Yet, the mechanisms that underlie NPM1 mediated phenotype remain elusive in the prostate. To better understand NPM1 functions in prostate cancer cells, we sought to characterize its impact on prostate cancer cells behaviour and decipher the mech ...[more]