3-(4-Fluoro-benzo-yl)-4-(4-fluoro-phen-yl)-4-hy-droxy-2,6-di-phenyl-cyclo-hexane-1,1-dicarbo-nitrile.

ABSTRACT: In the title compound, C33H24F2N2O2, the cyclo-hexane ring adopts a slightly distorted chair conformation. The dihedral angle between the planes of the phenyl rings is 71.80?(9)°, while the planes of the fluoro-phenyl and fluoro-benzoyl rings are inclined to one another by 31.04?(10)°. The dihedral angles between the planes of the phenyl ring adjacent to the 4-hydroxy group and those of the the fluoro-phenyl and fluoro-benzoyl rings are 51.64?(10) and 34.31?(10)°, respectively, while the corresponding angles for the phenyl ring adjacent to the 3-(4-fluorobenzoyl) group are 57.51?(9) and 85.02?(10)°, respectively. An intra-molecular O-H?O hydrogen bond generates an S(6) ring motif. In the crystal, mol-ecules are linked via pairs of O-H?N hydrogen bonds, forming inversion dimers. The dimers are linked via C-H?N and C-H?O hydrogen bonds, forming chains along the c-axis direction. C-H?F hydrogen bonds link the chains into sheets lying parallel to the bc plane.

SUBMITTER: Narayana B 

PROVIDER: S-EPMC4051101 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature