Ontology highlight
ABSTRACT:
SUBMITTER: Won TH
PROVIDER: S-EPMC4071600 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Won Tae Hyung TH You Minjung M Lee So-Hyoung SH Rho Boon Jo BJ Oh Dong-Chan DC Oh Ki-Bong KB Shin Jongheon J
Marine drugs 20140624 6
Seven new amino alcohol compounds, pseudoaminols A-G (1-7), were isolated from the ascidian Pseudodistoma sp. collected off the coast of Chuja-do, Korea. Structures of these new compounds were determined by analysis of the spectroscopic data and from chemical conversion. The presence of an N-carboxymethyl group in two of the new compounds (6 and 7) is unprecedented among amino alcohols. Several of these compounds exhibited moderate antimicrobial activity and cytotoxicity, as well as weak inhibit ...[more]