Ontology highlight
ABSTRACT:
SUBMITTER: Dahiya S
PROVIDER: S-EPMC4074542 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Dahiya Satinder S Irish Bryan P BP Nonnemacher Michael R MR Wigdahl Brian B
Advances in virus research 20130101
HIV-associated neurologic disease continues to be a significant complication in the era of highly active antiretroviral therapy. A substantial subset of the HIV-infected population shows impaired neuropsychological performance as a result of HIV-mediated neuroinflammation and eventual central nervous system (CNS) injury. CNS compartmentalization of HIV, coupled with the evolution of genetically isolated populations in the CNS, is responsible for poor prognosis in patients with AIDS, warranting f ...[more]