Dataset Information

PredictProtein--an open resource for online prediction of protein structural and functional features.

ABSTRACT: PredictProtein is a meta-service for sequence analysis that has been predicting structural and functional features of proteins since 1992. Queried with a protein sequence it returns: multiple sequence alignments, predicted aspects of structure (secondary structure, solvent accessibility, transmembrane helices (TMSEG) and strands, coiled-coil regions, disulfide bonds and disordered regions) and function. The service incorporates analysis methods for the identification of functional regions (ConSurf), homology-based inference of Gene Ontology terms (metastudent), comprehensive subcellular localization prediction (LocTree3), protein-protein binding sites (ISIS2), protein-polynucleotide binding sites (SomeNA) and predictions of the effect of point mutations (non-synonymous SNPs) on protein function (SNAP2). Our goal has always been to develop a system optimized to meet the demands of experimentalists not highly experienced in bioinformatics. To this end, the PredictProtein results are presented as both text and a series of intuitive, interactive and visually appealing figures. The web server and sources are available at http://ppopen.rostlab.org.

SUBMITTER: Yachdav G

PROVIDER: S-EPMC4086098 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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PredictProtein--an open resource for online prediction of protein structural and functional features.

Yachdav Guy G Kloppmann Edda E Kajan Laszlo L Hecht Maximilian M Goldberg Tatyana T Hamp Tobias T Hönigschmid Peter P Schafferhans Andrea A Roos Manfred M Bernhofer Michael M Richter Lothar L Ashkenazy Haim H Punta Marco M Schlessinger Avner A Bromberg Yana Y Schneider Reinhard R Vriend Gerrit G Sander Chris C Ben-Tal Nir N Rost Burkhard B

Nucleic acids research 20140505 Web Server issue

PredictProtein is a meta-service for sequence analysis that has been predicting structural and functional features of proteins since 1992. Queried with a protein sequence it returns: multiple sequence alignments, predicted aspects of structure (secondary structure, solvent accessibility, transmembrane helices (TMSEG) and strands, coiled-coil regions, disulfide bonds and disordered regions) and function. The service incorporates analysis methods for the identification of functional regions (ConSu ...[more]

PMID: 24799431

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Dataset Information

PredictProtein--an open resource for online prediction of protein structural and functional features.

Publications

PredictProtein--an open resource for online prediction of protein structural and functional features.

Similar Datasets

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