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Palladium-catalyzed arylation of cyanamides.

ABSTRACT: The cross-coupling of alkyl cyanamides with a number of aryl, heteroaryl, and vinyl halide and pseudohalide coupling partners has been developed via a modification of Pd-catalyzed amidation methods. The reactions proceed selectively under mild conditions with reasonable reaction times in moderate to excellent yields.

SUBMITTER: Stolley RM

PROVIDER: S-EPMC4113087 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Palladium-catalyzed arylation of cyanamides.

Stolley Ryan M RM Guo Wenxing W Louie Janis J

Organic letters 20111205 1

The cross-coupling of alkyl cyanamides with a number of aryl, heteroaryl, and vinyl halide and pseudohalide coupling partners has been developed via a modification of Pd-catalyzed amidation methods. The reactions proceed selectively under mild conditions with reasonable reaction times in moderate to excellent yields. ...[more]

PMID: 22142553

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