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Palladium-catalyzed arylation and heteroarylation of indolizines.

ABSTRACT: A highly effective protocol for palladium-catalyzed selective arylation and heteroarylation of indolizines at C-3 has been developed. Mechanistic studies unambiguously support an electrophilic substitution pathway for this transformation.

SUBMITTER: Park CH

PROVIDER: S-EPMC3708550 | biostudies-literature | 2004 Apr

REPOSITORIES: biostudies-literature

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Palladium-catalyzed arylation and heteroarylation of indolizines.

Park Choul-Hong CH Ryabova Victoria V Seregin Ilya V IV Sromek Anna W AW Gevorgyan Vladimir V

Organic letters 20040401 7

A highly effective protocol for palladium-catalyzed selective arylation and heteroarylation of indolizines at C-3 has been developed. Mechanistic studies unambiguously support an electrophilic substitution pathway for this transformation. ...[more]

PMID: 15040747

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