Ontology highlight
ABSTRACT:
SUBMITTER: Hamlin AM
PROVIDER: S-EPMC4120980 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20140711 15
The full details of a synthesis of the hetidine framework of the C20-diterpenoid alkaloids and its conversion to the atisine core structure are reported. The application of the hetidine framework to the synthesis of dihydronavirine, which is the formal reduction product of the natural product navirine, is also described. Key to the success of these studies is the use of a Ga(III)-catalyzed cycloisomerization reaction of alkynylindenes to prepare a [6-7-6] framework that was advanced to the hetid ...[more]