Ontology highlight
ABSTRACT:
SUBMITTER: Rajanala K
PROVIDER: S-EPMC4141044 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Rajanala Kalpana K Sarkar Anshuk A Jhingan Gagan Deep GD Priyadarshini Raina R Jalan Manisha M Sengupta Sagar S Nandicoori Vinay Kumar VK
Journal of cell science 20140617 Pt 16
A major constituent of the nuclear basket region of the nuclear pore complex (NPC), nucleoporin Tpr, plays roles in regulating multiple important processes. We have previously established that Tpr is phosphorylated in both a MAP-kinase-dependent and MAP-kinase-independent manner, and that Tpr acts as both a substrate and as a scaffold for ERK2 (also known as MAPK1). Here, we report the identification of S2059 and S2094 as the major novel ERK-independent phosphorylation sites and T1677, S2020, S2 ...[more]