Dataset Information
Facile synthesis of (+/-)-paeonilide.
Ontology highlight
ABSTRACT:
SUBMITTER: Du Y
PROVIDER: S-EPMC4142627 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Publications
Facile synthesis of (+/-)-paeonilide.
The Journal of organic chemistry 20070406 10
(+/-)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis. ...[more]