Ontology highlight
ABSTRACT:
SUBMITTER: Malet H
PROVIDER: S-EPMC4145799 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Malet Hélène H Liu Kaiyin K El Bakkouri Majida M Chan Sze Wah Samuel SW Effantin Gregory G Bacia Maria M Houry Walid A WA Gutsche Irina I
eLife 20140805
A 3.3 MDa macromolecular cage between two Escherichia coli proteins with seemingly incompatible symmetries-the hexameric AAA+ ATPase RavA and the decameric inducible lysine decarboxylase LdcI-is reconstructed by cryo-electron microscopy to 11 Å resolution. Combined with a 7.5 Å resolution reconstruction of the minimal complex between LdcI and the LdcI-binding domain of RavA, and the previously solved crystal structures of the individual components, this work enables to build a reliable pseudoato ...[more]