Ontology highlight
ABSTRACT:
SUBMITTER: Park TS
PROVIDER: S-EPMC4156757 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Park Tae Sub TS Lee Hong Jo HJ Kim Ki Hyun KH Kim Jin-Soo JS Han Jae Yong JY
Proceedings of the National Academy of Sciences of the United States of America 20140819 35
Genetically modified animals are used for industrial applications as well as scientific research, and studies on these animals contribute to a better understanding of biological mechanisms. Gene targeting techniques have been developed to edit specific gene loci in the genome, but the conventional strategy of homologous recombination with a gene-targeted vector has low efficiency and many technical complications. Here, we generated specific gene knockout chickens through the use of transcription ...[more]