Ontology highlight
ABSTRACT:
SUBMITTER: Stahli A
PROVIDER: S-EPMC4157743 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Stähli Alexandra A Bosshardt Dieter D Sculean Anton A Gruber Reinhard R
PloS one 20140908 9
Genome-wide microarrays have suggested that Emdogain regulates TGF-β target genes in gingival and palatal fibroblasts. However, definitive support for this contention and the extent to which TGF-β signaling contributes to the effects of Emdogain has remained elusive. We therefore studied the role of the TGF-β receptor I (TGF-βRI) kinase to mediate the effect of Emdogain on palatal fibroblasts. Palatal fibroblasts were exposed to Emdogain with and without the inhibitor for TGF-βRI kinase, SB43154 ...[more]