Ontology highlight
ABSTRACT:
SUBMITTER: Tuyishime S
PROVIDER: S-EPMC4219370 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Tuyishime Steven S Haut Larissa H LH Zhu Caihong C Ertl Hildegund C J HC
Vaccine 20140426 27
Vaccination is an important tool for enhancing immune responses against mucosal pathogens. Intramuscularly administered adenovirus (Ad) vectors have been demonstrated to be strong inducers of both systemic and mucosal immune responses. Further enhancement of immune responses following Ad vaccination is highly desirable. All-trans retinoic acid (ATRA), a biologically active vitamin A metabolite, has been explored as an adjuvant for primary immune responses following vaccination. In this study, we ...[more]