Ontology highlight
ABSTRACT:
SUBMITTER: Hogarth P
PROVIDER: S-EPMC4298713 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Journal of movement disorders 20150113 1
Neurodegeneration with brain iron accumulation (NBIA) encompasses a group of inherited disorders that share the clinical features of an extrapyramidal movement disorder accompanied by varying degrees of intellectual disability and abnormal iron deposition in the basal ganglia. The genetic basis of ten forms of NBIA is now known. The clinical features of NBIA range from rapid global neurodevelopmental regression in infancy to mild parkinsonism with minimal cognitive impairment in adulthood, with ...[more]