Ontology highlight
ABSTRACT:
SUBMITTER: Kaniskan HU
PROVIDER: S-EPMC4301070 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
ACS chemical biology 20141125 1
Growing evidence suggests that histone methyltransferases (HMTs, also known as protein methyltransferases (PMTs)) play an important role in diverse biological processes and human diseases by regulating gene expression and the chromatin state. Therefore, HMTs have been increasingly recognized by the biomedical community as a class of potential therapeutic targets. High quality chemical probes of HMTs, as tools for deciphering their physiological functions and roles in human diseases and testing t ...[more]