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Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid.

ABSTRACT: Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 ?M with a limit of detection of 0.512 ?M.

SUBMITTER: Wang L

PROVIDER: S-EPMC4320994 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid.

Wang Lei L Sibrian-Vazquez Martha M Escobedo Jorge O JO Wang Jialu J Moore Richard G RG Strongin Robert M RM

Chemical communications (Cambridge, England) 20150101 9

Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 μM with a limit of detection of 0.512 μM. ...[more]

PMID: 25516957

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