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One-pot, three-component arylalkynyl sulfone synthesis.

ABSTRACT: A one-pot three-component protocol for the preparation of arylsulfonyl alkynes through the reaction of ethynyl-benziodoxolone (EBX) reagents, DABSO (DABCO·SO2), and either organomagnesium reagents or aryl iodides with a palladium catalyst is reported. A broad range of aryl and heteroarylalkynyl sulfones were obtained in 46-85% overall yield.

SUBMITTER: Chen CC

PROVIDER: S-EPMC4342956 | biostudies-literature |

REPOSITORIES: biostudies-literature

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