Ontology highlight
ABSTRACT:
SUBMITTER: MacRaild CA
PROVIDER: S-EPMC4351039 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
MacRaild Christopher A CA Zachrdla Milan M Andrew Dean D Krishnarjuna Bankala B Nováček Jiří J Žídek Lukáš L Sklenář Vladimír V Richards Jack S JS Beeson James G JG Anders Robin F RF Norton Raymond S RS
PloS one 20150305 3
Merozoite surface protein 2 (MSP2) of Plasmodium falciparum is an abundant, intrinsically disordered protein that is GPI-anchored to the surface of the invasive blood stage of the malaria parasite. Recombinant MSP2 has been trialled as a component of a malaria vaccine, and is one of several disordered proteins that are candidates for inclusion in vaccines for malaria and other diseases. Nonetheless, little is known about the implications of protein disorder for the development of an effective an ...[more]