Structural biology of TRP channels.
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ABSTRACT:
SUBMITTER: Li M
PROVIDER: S-EPMC4356010 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Structural biology of TRP channels.
Li Minghui M Yu Yong Y Yang Jian J
Advances in experimental medicine and biology 20110101
Structural studies on TRP channels, while limited, are poised for a quickened pace and rapid expansion. As of yet, no high-resolution structure of a full length TRP channel exists, but low-resolution electron cryomicroscopy structures have been obtained for 4 TRP channels, and high-resolution NMR and X-ray crystal structures have been obtained for the cytoplasmic domains, including an atypical protein kinase domain, ankyrin repeats, coiled coil domains and a Ca(2+)-binding domain, of 6 TRP chann ...[more]
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