Ontology highlight
ABSTRACT:
SUBMITTER: El-Elimat T
PROVIDER: S-EPMC4372511 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
El-Elimat Tamam T Raja Huzefa A HA Figueroa Mario M Swanson Steven M SM Falkinham Joseph O JO Lucas David M DM Grever Michael R MR Wani Mansukh C MC Pearce Cedric J CJ Oberlies Nicholas H NH
The Journal of antibiotics 20140924 3
As part of an ongoing project to explore filamentous fungi for anticancer and antibiotic leads, 11 compounds were isolated and identified from an organic extract of the fungus Scytalidium album (MSX51631) using bioactivity-directed fractionation against human cancer cell lines. Of these, eight compounds were a series of sorbicillinoid analogs (1-8), of which four were new (scalbucillin A (2), scalbucillin B (3), scalbucillin C (6) and scalbucillin D (8)), two were phthalides (9-10) and one was n ...[more]