Ontology highlight
ABSTRACT:
SUBMITTER: Pickett JE
PROVIDER: S-EPMC4385467 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Bioorganic & medicinal chemistry letters 20150302 8
Trialkylstannanes are versatile precursors for chemical transformations, including radiolabeling with a variety of halogens, particularly iodine. In the present work a convenient, Pd-mediated stannylation method is presented that can be performed in an open flask. The method is selective for aryl iodides allowing selective stannylations in the presence of other halogen atoms. The reaction conditions are mild, making the method compatible with chemically sensitive bioactive compounds. ...[more]