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Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes.

ABSTRACT: We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)2 and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.

SUBMITTER: Dian L

PROVIDER: S-EPMC7493299 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes.

Dian Longyang L Marek Ilan I

ACS catalysis 20191226 2

We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)<sub>2</sub> and (<i>R</i>)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities. ...[more]

PMID: 32953232

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