Ontology highlight
ABSTRACT:
SUBMITTER: Sun H
PROVIDER: S-EPMC4419545 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20150422
The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type ring opening followed by cyclization of the resulting haloalkoxy amine. ...[more]