Ontology highlight
ABSTRACT:
SUBMITTER: Reinitz A
PROVIDER: S-EPMC4426013 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Reinitz Adam A DeStefano Jackson J Ye Mao M Wong Andrew D AD Searson Peter C PC
Microvascular research 20150226
Endothelial cells in straight sections of vessels are known to elongate and align in the direction of flow. This phenotype has been replicated in confluent monolayers of bovine aortic endothelial cells and human umbilical vein endothelial cells (HUVECs) in cell culture under physiological shear stress. Here we report on the morphological response of human brain microvascular endothelial cells (HBMECs) in confluent monolayers in response to shear stress. Using a microfluidic platform we image con ...[more]