Ontology highlight
ABSTRACT:
SUBMITTER: Stockdill JL
PROVIDER: S-EPMC4446722 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Tetrahedron letters 20150601 23
The <i>Daphniphyllum</i> alkaloids remain an attractive target in the synthetic community because of their unique framework and promising biological activities. We have shown that the ABC core of the calyciphylline A-type alkaloids can be rapidly accessed via the tandem cyclization of a neutral aminyl radical with a polarized cyclic olefin. Deuterium labeling experiments and reactions omitting a tin hydride reagent suggest that the solvent is the major source of the terminating hydrogen atom in ...[more]