Ontology highlight
ABSTRACT:
SUBMITTER: Sampath V
PROVIDER: S-EPMC4465440 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Sampath V V Mulrooney N P NP Garland J S JS He J J Patel A L AL Cohen J D JD Simpson P M PM Hines R N RN
Journal of perinatology : official journal of the California Perinatal Association 20130718 10
<h4>Objective</h4>To test the hypothesis that single-nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes alter susceptibility to bacterial infections and modulate white blood cell (WBC) counts during infections in very low birth weight (VLBW) infants (birth weight <1500 g).<h4>Study design</h4>VLBW infants recruited in a multicenter study were genotyped for nine functional TLR SNPs and associations between SNPs and infection rates examined. WBC counts obtained during infections wer ...[more]