Ontology highlight
ABSTRACT:
SUBMITTER: Mather W
PROVIDER: S-EPMC4494757 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Mather William W Hasty Jeff J Tsimring Lev S LS
Physical review letters 20140916 12
The development of synthetic gene oscillators has not only demonstrated our ability to forward engineer reliable circuits in living cells, but it has also proven to be an excellent testing ground for the statistical behavior of coupled noisy oscillators. Previous experimental studies demonstrated that a shared positive feedback can reliably synchronize such oscillators, though the theoretical mechanism was not studied in detail. In the present work, we examine an experimentally motivated stochas ...[more]