Ontology highlight
ABSTRACT:
SUBMITTER: Hotamisligil GS
PROVIDER: S-EPMC4578711 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hotamisligil Gökhan S GS Bernlohr David A DA
Nature reviews. Endocrinology 20150811 10
Intracellular and extracellular interactions with proteins enables the functional and mechanistic diversity of lipids. Fatty acid-binding proteins (FABPs) were originally described as intracellular proteins that can affect lipid fluxes, metabolism and signalling within cells. As the functions of this protein family have been further elucidated, it has become evident that they are critical mediators of metabolism and inflammatory processes, both locally and systemically, and therefore are potenti ...[more]