Ontology highlight
ABSTRACT:
SUBMITTER: Dong L
PROVIDER: S-EPMC4620443 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Dong Lili L Tan Qiwen Q Ye Wei W Liu Dongli D Chen Haifeng H Hu Hongwei H Wen Duo D Liu Yang Y Cao Ya Y Kang Jingwu J Fan Jia J Guo Wei W Wu Weizhong W
Scientific reports 20151026
Alpha-fetoprotein (AFP) is a liver cancer associated protein and has long been utilized as a serum tumor biomarker of disease progression. AFP is usually detected in HCC patients by an antibody based system. Recently, however, aptamers generated from systematic evolution of ligands by exponential enrichment (SELEX) were reported to have an alternative potential in targeted imaging, diagnosis and therapy. In this study, AFP-bound ssDNA aptamers were screened and identified using capillary electro ...[more]