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In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium.

ABSTRACT: In vitro susceptibilities of a worldwide collection of molecularly identified Phaeoacremonium strains (n = 43) belonging to seven species and originating from human and environmental sources were determined for eight antifungal drugs. Voriconazole had the lowest geometric mean MIC (0.35 ?g/ml), followed by posaconazole (0.37 ?g/ml), amphotericin B (0.4 ?g/ml), and isavuconazole (1.16 ?g/ml). Caspofungin, anidulafungin, fluconazole, and itraconazole had no activity.

SUBMITTER: Badali H

PROVIDER: S-EPMC4649167 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium.

Badali Hamid H Khodavaisy Sadegh S Fakhim Hamed H de Hoog G Sybren GS Meis Jacques F JF Chowdhary Anuradha A

Antimicrobial agents and chemotherapy 20150914 12

In vitro susceptibilities of a worldwide collection of molecularly identified Phaeoacremonium strains (n = 43) belonging to seven species and originating from human and environmental sources were determined for eight antifungal drugs. Voriconazole had the lowest geometric mean MIC (0.35 μg/ml), followed by posaconazole (0.37 μg/ml), amphotericin B (0.4 μg/ml), and isavuconazole (1.16 μg/ml). Caspofungin, anidulafungin, fluconazole, and itraconazole had no activity. ...[more]

PMID: 26369976

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