Ontology highlight
ABSTRACT:
SUBMITTER: Marenholz I
PROVIDER: S-EPMC4667629 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Nature communications 20151106
Eczema often precedes the development of asthma in a disease course called the 'atopic march'. To unravel the genes underlying this characteristic pattern of allergic disease, we conduct a multi-stage genome-wide association study on infantile eczema followed by childhood asthma in 12 populations including 2,428 cases and 17,034 controls. Here we report two novel loci specific for the combined eczema plus asthma phenotype, which are associated with allergic disease for the first time; rs9357733 ...[more]