Ontology highlight
ABSTRACT:
SUBMITTER: Cong P
PROVIDER: S-EPMC4675846 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Cong Peiwen P Dai Liang L Chen Hu H van der Maarel Johan R C JR Doyle Patrick S PS Yan Jie J
Biophysical journal 20151201 11
Several recent experiments suggest that sharply bent DNA has a surprisingly high bending flexibility, but the cause of this flexibility is poorly understood. Although excitation of flexible defects can explain these results, whether such excitation can occur with the level of DNA bending in these experiments remains unclear. Intriguingly, the DNA contained preexisting nicks in most of these experiments but whether nicks might play a role in flexibility has never been considered in the interpreta ...[more]