Ontology highlight
ABSTRACT:
SUBMITTER: Stephens DE
PROVIDER: S-EPMC4714569 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Stephens David E DE Lakey-Beitia Johant J Chavez Gabriel G Ilie Carla C Arman Hadi D HD Larionov Oleg V OV
Chemical communications (Cambridge, England) 20150601 46
A novel site-selective palladium-catalyzed oxidative C8-H homocoupling reaction of quinoline N-oxides has been developed. The reaction affords substituted 8,8'-biquinolyl N,N'-dioxides that can be readily converted to a variety of functionalized 8,8'-biquinolyls. Mechanistic studies point to the crucial role of the oxidant and a non-innocent behavior of acetic acid as a solvent. ...[more]