Ontology highlight
ABSTRACT:
SUBMITTER: Newcomb ET
PROVIDER: S-EPMC4732274 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Newcomb Eric T ET Knutson Phil C PC Pedersen Blaine A BA Ferreira Eric M EM
Journal of the American Chemical Society 20151230 1
The first total synthesis of (±)-gelsenicine is reported. The synthetic route is highly efficient (13 steps), featuring (1) a pivotal metal-catalyzed isomerization/rearrangement process that forges the central core of the molecule and (2) two facile C-N bond-forming steps that establish the flanking heterocycles. ...[more]