Familial Risk for Exceptional Longevity.
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ABSTRACT:
SUBMITTER: Sebastiani P
PROVIDER: S-EPMC4812435 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Familial Risk for Exceptional Longevity.
Sebastiani Paola P Andersen Stacy L SL McIntosh Avery I AI Nussbaum Lisa L Stevenson Meredith D MD Pierce Leslie L Xia Samantha S Salance Kelly K Perls Thomas T TT
North American actuarial journal : NAAJ 20151007 1
One of the most glaring deficiencies in the current assessment of mortality risk is the lack of information concerning the impact of familial longevity. In this work, we update estimates of sibling relative risk of living to extreme ages using data from more than 1,700 sibships, and we begin to examine the trend for heritability for different birth-year cohorts. We also build a network model that can be used to compute the increased chance for exceptional longevity of a subject, conditional on h ...[more]
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