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A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging.

ABSTRACT: A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse.

SUBMITTER: Liu Z

PROVIDER: S-EPMC4928191 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging.

Liu Zonglun Z Gao Kuo K Wang Beng B Yan Hui H Xing Panfei P Zhong Chongmin C Xu Yongqian Y Li Hongjuan H Chen Jianxin J Wang Wei W Sun Shiguo S

Scientific reports 20160630

A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse. ...[more]

PMID: 27356618

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