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Imaging gene expression in single living cells.

ABSTRACT: Technical advances in the field of live-cell imaging have introduced the cell biologist to a new, dynamic, subcellular world. The static world of molecules in fixed cells has now been extended to the time dimension. This allows the visualization and quantification of gene expression and intracellular trafficking events of the studied molecules and the associated enzymatic processes in individual cells, in real time.

SUBMITTER: Shav-Tal Y

PROVIDER: S-EPMC4942131 | biostudies-literature | 2004 Oct

REPOSITORIES: biostudies-literature

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Imaging gene expression in single living cells.

Shav-Tal Yaron Y Singer Robert H RH Darzacq Xavier X

Nature reviews. Molecular cell biology 20041001 10

Technical advances in the field of live-cell imaging have introduced the cell biologist to a new, dynamic, subcellular world. The static world of molecules in fixed cells has now been extended to the time dimension. This allows the visualization and quantification of gene expression and intracellular trafficking events of the studied molecules and the associated enzymatic processes in individual cells, in real time. ...[more]

PMID: 15459666

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