Ontology highlight
ABSTRACT:
SUBMITTER: Choi S
PROVIDER: S-EPMC4981534 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Choi Sungkyoung S Lee Sungyoung S Qiao Dandi D Hardin Megan M Cho Michael H MH Silverman Edwin K EK Park Taesung T Won Sungho S
Genetic epidemiology 20160621 6
Although the X chromosome has many genes that are functionally related to human diseases, the complicated biological properties of the X chromosome have prevented efficient genetic association analyses, and only a few significantly associated X-linked variants have been reported for complex traits. For instance, dosage compensation of X-linked genes is often achieved via the inactivation of one allele in each X-linked variant in females; however, some X-linked variants can escape this X chromoso ...[more]