Identification of human RNA editing sites: A historical perspective.
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ABSTRACT:
SUBMITTER: Ramaswami G
PROVIDER: S-EPMC5014717 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Identification of human RNA editing sites: A historical perspective.
Ramaswami Gokul G Li Jin Billy JB
Methods (San Diego, Calif.) 20160518
A-to-I RNA editing is an essential gene regulatory mechanism. Once thought to be a rare phenomenon only occurring in a few transcripts, the emergence of high-throughput RNA sequencing has facilitated the identification of over 2 million RNA editing sites in the human transcriptome. In this review, we survey the current RNA-seq based methods as well as historical methods used to identify RNA editing sites. ...[more]
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