Ontology highlight
ABSTRACT:
SUBMITTER: Ni X
PROVIDER: S-EPMC5041480 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Ni Xiaodan X Davis Joseph H JH Jain Nikhil N Razi Aida A Benlekbir Samir S McArthur Andrew G AG Rubinstein John L JL Britton Robert A RA Williamson James R JR Ortega Joaquin J
Nucleic acids research 20160802 17
YphC and YsxC are GTPases in Bacillus subtilis that facilitate the assembly of the 50S ribosomal subunit, however their roles in this process are still uncharacterized. To explore their function, we used strains in which the only copy of the yphC or ysxC genes were under the control of an inducible promoter. Under depletion conditions, they accumulated incomplete ribosomal subunits that we named 45SYphC and 44.5SYsxC particles. Quantitative mass spectrometry analysis and the 5-6 Å resolution cry ...[more]