Ontology highlight
ABSTRACT:
SUBMITTER: Cao L
PROVIDER: S-EPMC5059455 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Cao Lixue L Huang Qiao Q Wu Zhichao Z Cao Dong-Dong DD Ma Zhanling Z Xu Qianghua Q Hu Peng P Fu Yanxia Y Shen Yu Y Chan Jiulin J Zhou Cong-Zhao CZ Zhai Wanying W Chen Liangbiao L
Nature communications 20161004
The mechanisms by which the eggs of the Antarctic notothenioid fishes avoid freezing are not fully understood. Zona pellucida proteins (ZPs) are constituents of the chorion which forms a protective matrix surrounding the egg. Here we report occurrence of freezing temperature-related gene expansion and acquisition of unusual ice melting-promoting (IMP) activity in a family of Antarctic notothenioid ZPs (AnnotoZPs). Members of AnnotoZPs are shown to bind with ice and non-colligatively depress the ...[more]