Ontology highlight
ABSTRACT:
SUBMITTER: Rosa S
PROVIDER: S-EPMC5059766 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Rosa Stefanie S Duncan Susan S Duncan Susan S Dean Caroline C
Nature communications 20161007
Antisense transcription through genic regions is pervasive in most genomes; however, its functional significance is still unclear. We are studying the role of antisense transcripts (COOLAIR) in the cold-induced, epigenetic silencing of Arabidopsis FLOWERING LOCUS C (FLC), a regulator of the transition to reproduction. Here we use single-molecule RNA FISH to address the mechanistic relationship of FLC and COOLAIR transcription at the cellular level. We demonstrate that while sense and antisense t ...[more]