Ontology highlight
ABSTRACT:
SUBMITTER: Dadhania V
PROVIDER: S-EPMC5078592 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
EBioMedicine 20160825
<h4>Background</h4>It has been suggested that bladder cancer can be divided into two molecular subtypes referred to as luminal and basal with distinct clinical behaviors and sensitivities to chemotherapy. We aimed to validate these subtypes in several clinical cohorts and identify signature immunohistochemical markers that would permit simple and cost-effective classification of the disease in primary care centers.<h4>Methods</h4>We analyzed genomic expression profiles of bladder cancer in three ...[more]