Ontology highlight
ABSTRACT:
SUBMITTER: Gan Q
PROVIDER: S-EPMC5180212 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Gan Qinglei Q Lehman Brent P BP Bobik Thomas A TA Fan Chenguang C
Scientific reports 20161223
The diversity of non-canonical amino acids (ncAAs) endows proteins with new features for a variety of biological studies and biotechnological applications. The genetic code expansion strategy, which co-translationally incorporates ncAAs into specific sites of target proteins, has been applied in many organisms. However, there have been only few studies on pathogens using genetic code expansion. Here, we introduce this technique into the human pathogen Salmonella by incorporating p-azido-phenylal ...[more]